Mutational status of naevus-associated melanomas
نویسندگان
چکیده
منابع مشابه
Mutational status of naevus-associated melanomas.
BACKGROUND The origin of melanoma has always been a debated subject, as well as the role of adjacent melanocytic naevi. Epidemiological and histopathological studies point to melanomas arising either de novo or from a naevus. OBJECTIVES To evaluate the presence of mutations in genes from well-known melanomagenesis pathways in a large series of naevus-associated melanomas. MATERIALS AND METH...
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Sir, Becker's naevus or Becker's melanosis is a relatively common disorder, which appears as a hyperpigmented, hypertrichotic patch located mainly on the trunk (1). Becker's naevus has been associated with various soft tissue and bony structural anomalies, such as hypoplasia of the ipsilateral breast, pectoralis major muscle, leg, arm and contralateral breast, spina bi®da, and pectus carinatum ...
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ژورنال
عنوان ژورنال: British Journal of Dermatology
سال: 2015
ISSN: 0007-0963
DOI: 10.1111/bjd.13829